
The Maudsley Prescribing Guidelines in Psychiatry
by Taylor, David; Paton, Carol; Kapur, ShitijRent Textbook
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Summary
Author Biography
Table of Contents
Preface | p. ix |
Acknowledgements | p. x |
Notes on using The Maudsley Prescribing Guidelines | p. xi |
Notes on inclusion of drugs | p. xi |
List of abbreviations | p. xii |
Plasma level monitoring of psychotropic drugs and anticonvulsants | p. 1 |
Interpreting sample results | p. 2 |
Schizophrenia | p. 11 |
Antipsychotic drugs | p. 11 |
Antipsychotic drugs: equivalent doses | p. 13 |
Antipsychotic drugs: minimum effective doses | p. 14 |
Antipsychotic drugs: licensed maximum doses | p. 16 |
New antipsychotic drugs | p. 17 |
Antipsychotic drugs: general principles of prescribing | p. 21 |
National Institute for Health and Clinical Excellence guidelines for the treatment of schizophrenia | p. 22 |
Treatment algorithms for schizophrenia | p. 24 |
Antipsychotic drugs: monitoring of metabolic effects | p. 26 |
Switching antipsychotic drugs because of poor tolerability | p. 31 |
Antipsychotic response: to increase the dose, to switch, to add or just wait-what is the right move? | p. 33 |
Speed and onset of antipsychotic drug action | p. 36 |
First-generation antipsychotic drugs: place in therapy | p. 39 |
Antipsychotic drugs: long-acting injections | p. 40 |
Risperidone long-acting injection | p. 44 |
Paliperidone palmitate long-acting injection | p. 47 |
Management of patients on long-term depots: dose reduction | p. 50 |
Combined antipsychotic drugs | p. 51 |
High-dose antipsychotic drugs: prescribing and monitoring | p. 54 |
Negative symptoms in schizophrenia | p. 57 |
Antipsychotic prophylaxis | p. 60 |
Refractory schizophrenia and clozapine | p. 64 |
Clozapine augmentation | p. 66 |
Refractory schizophrenia: alternatives to clozapine | p. 69 |
Clozapine: management of common adverse effects | p. 75 |
Clozapine: uncommon or unusual adverse effects | p. 78 |
Clozapine: serious haematological and cardiovascular adverse effects | p. 80 |
Clozapine, neutropenia and lithium | p. 84 |
Clozapine and chemotherapy | p. 88 |
Clozapine-related hypersalivation | p. 89 |
Guidelines for the initiation of clozapine for patients based in the community | p. 92 |
Omega-3 fatty acids fish oils in schizophrenia | p. 96 |
Extrapyramidal side-effects of antipsychotic drug treatment | p. 98 |
Treatment of antipsychotic-induced akathisia | p. 103 |
Treatment of tardive dyskinesia | p. 105 |
Neuroleptic malignant syndrome | p. 110 |
Catatonia | p. 113 |
Cardiovascular effects of antipsychotic drug treatment | p. 115 |
Antipsychotic drugs and hypertension | p. 122 |
Hyperprolactinaemia | p. 123 |
Antipsychotic-induced weight gain | p. 126 |
Treatment of drug-induced weight gain | p. 128 |
Antipsychotic drugs, diabetes and impaired glucose tolerance | p. 132 |
Antipsychotic drugs and dyslipidaemia | p. 138 |
Antipsychotic drugs and sexual dysfunction | p. 142 |
Antipsychotic-associated hyponatraemia | p. 148 |
Antipsychotics and pneumonia | p. 150 |
Relative adverse effects of antipsychotic drugs: a rough guide | p. 151 |
Bipolar disorder | p. 153 |
Valproate | p. 153 |
Lithium | p. 159 |
Carbamazepine | p. 168 |
Physical monitoring of people with bipolar disorder | p. 173 |
Treatment of acute mania or hypomania | p. 176 |
Antipsychotic drugs in bipolar disorder | p. 182 |
Bipolar depression | p. 185 |
Rapid cycling bipolar disorder | p. 191 |
Prophylaxis in bipolar disorder | p. 193 |
Depression and anxiety | p. 197 |
Depression | p. 197 |
Antidepressants | p. 201 |
Treatment of resistant depression | p. 222 |
Treatment of psychotic depression | p. 233 |
Electroconvulsive therapy and psychotropic drugs | p. 235 |
Psychostimulants in depression | p. 239 |
Treatment of depression in the elderly | p. 243 |
Treatment of depression in stroke | p. 247 |
Adverse effects of antidepressants | p. 249 |
Selective serotonin reuptake inhibitors and bleeding | p. 252 |
Depression and diabetes | p. 255 |
Cardiac effects of antidepressants | p. 257 |
Antidepressants and sexual dysfunction | p. 264 |
Antidepressants and hyperprolactinaemia | p. 268 |
Antidepressants: swapping and stopping | p. 270 |
St John's wort in the treatment of depression | p. 278 |
Drug interactions with antidepressants | p. 281 |
Alternative routes of administration for antidepressants | p. 286 |
Anxiety spectrum disorders | p. 292 |
Benzodiazepines in the treatment of psychiatric disorders | p. 301 |
Benzodiazepines and disinhibition | p. 304 |
Benzodiazepines: dependence and detoxification306 | |
Insomnia | p. 310 |
Children and adolescents | p. 315 |
Principles of prescribing practice in childhood and adolescence | p. 315 |
Depression in children and adolescents | p. 316 |
Bipolar illness in children and adolescents | p. 321 |
Psychosis in children and adolescents | p. 326 |
Anxiety in children and adolescents | p. 327 |
Obsessive compulsive disorder in children and adolescents | p. 328 |
Attention deficit hyperactivity disorder | p. 332 |
Autism spectrum disorders | p. 337 |
Tics and Tourette's syndrome | p. 345 |
Melatonin in the treatment of insomnia in children and adolescents | p. 349 |
Rapid tranquillisation in children and adolescents | p. 351 |
Doses of commonly used psychotropic drugs in children and adolescents | p. 354 |
Substance misuse | p. 355 |
Alcohol dependence | p. 356 |
Opioid misuse and dependence | p. 372 |
Nicotine and smoking cessation | p. 398 |
Stimulant drugs of dependence | p. 406 |
Benzodiazepine misuse | p. 407 |
¿ -Butaryl-lactone and ¿ -hydroxybutyrate dependence | p. 408 |
Drugs of misuse: a summary | p. 410 |
Interactions between 'street drugs' and prescribed psychotropic drugs | p. 414 |
Use of psychotropic drugs in special patient groups | p. 419 |
Epilepsy | p. 419 |
Pregnancy | p. 430 |
Breast feeding | p. 446 |
Renal impairment | p. 462 |
Hepatic impairment | p. 478 |
Prescribing in the elderly | p. 487 |
Dementia | p. 490 |
Behavioural and psychological symptoms of dementia | p. 509 |
Parkinson's disease | p. 518 |
Multiple sclerosis | p. 522 |
Eating disorders | p. 527 |
Acutely disturbed or violent behaviour | p. 531 |
Psychotropic medications for adults with learning disabilities | p. 539 |
Borderline personality disorder | p. 545 |
Delirium | p. 547 |
Huntington's disease | p. 554 |
Psychotropic drugs and surgery | p. 558 |
Prescribing psychotropic drugs for patients with HIV infection | p. 564 |
Psychotropic drugs and cytochrome CYP function | p. 573 |
Summary of psychiatric side-effects of non-psychotropic drugs | p. 578 |
Miscellaneous conditions and substances | p. 587 |
Psychotropic drugs in overdose | p. 587 |
Biochemical and haematological effects of psychotropic drugs | p. 593 |
Prescribing drugs outside their licensed indications | p. 604 |
Observations on the placebo effect in mental illness | p. 606 |
Drug interactions with alcohol | p. 608 |
Nicotine | p. 613 |
Smoking and psychotropic drugs | p. 616 |
Caffeine | p. 618 |
Complementary therapies | p. 624 |
Enhancing medication adherence | p. 628 |
Driving and psychotropic medicines | p. 634 |
Covert administration of medicines within food and drink | p. 643 |
Index | p. 647 |
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